Open AccessResearch on coherent anti-Stokes Raman scattering microscopy
Author(s) -
Liu Shuang-Long,
Wei Liu,
Danni Chen,
Jingping Qü,
Hanben Niu
Publication year - 2016
Publication title -
wuli xuebao
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.199
H-Index - 47
ISSN - 1000-3290
DOI - 10.7498/aps.65.064204
Subject(s) - raman scattering , polystyrene , raman spectroscopy , materials science , optics , microscope , full width at half maximum , microscopy , resolution (logic) , coherent anti stokes raman spectroscopy , realization (probability) , optical microscope , scattering , point spread function , scanning electron microscope , physics , computer science , polymer , statistics , mathematics , artificial intelligence , composite material
In this paper, we analyze the process of coherent anti-Stokes Raman scattering (CARS) based on quantum theory and set up a traditional point-scanning CARS microscope. With this microscope, high-contrast images of polystyrene microspheres are obtained. By scanning polystyrene beads with 110 nm diameter, we reconstruct the point spread faction (PSF) of the system. And the full width at half maximum (FWHM) of the PSF shows a lateral resolution about 600 nm, which is larger than the theoretical value ( 300 nm). Therefore, we propose several resolution-improvement approaches, which lay a strong foundation for the realization of nano-CARS microscopy.