Open AccessCalcium ion spiral wave induced by random calcium ion sparks in single heart cell
Author(s) -
Yanping Bai,
Zhu Xing
Publication year - 2012
Publication title -
wuli xuebao
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.199
H-Index - 47
ISSN - 1000-3290
DOI - 10.7498/aps.61.158203
Subject(s) - calcium , ion , spiral (railway) , atomic physics , materials science , phase (matter) , singularity , physics , quantum mechanics , mathematics , mathematical analysis , metallurgy
Calcium ion spiral wave induced by random released calcium ion sparks in single heart cell is studied using the improved discrete fire-diffuse-fire model and phase analysis method. The results show that calcium ion spiral wave can be excited in resting heart cell by calcium ion sparks at an appropriate release frequency. The key of the generation of calcium ion spiral wave is the emergence of the phase singularity caused by the calcium sparks in the different time and space sequences. The number of phase singularity is exponentially linked with calcium ion spark frequency, and has the limit in a fixed system.