Open AccessInvestigation of bubble dynamics in ultrasonic sonoporation
Author(s) -
Qian Chen,
XinYe Zou,
Jianchun Cheng
Publication year - 2006
Publication title -
wuli xuebao
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.199
H-Index - 47
ISSN - 1000-3290
DOI - 10.7498/aps.55.6476
Subject(s) - cavitation , sonoporation , ultrasonic sensor , bubble , acoustics , radius , signal (programming language) , materials science , mechanics , viscosity , ultrasound , sonochemistry , vibration , sound pressure , microbubbles , physics , computer science , composite material , computer security , programming language
During the process of quickly producing pathologic sections of the living tissues with ultrasonic sonoporation, it has been found that the exciting ultrasonic signal has an evident effect on the pathologic section. For the sake of understanding the effect and obtaining the best state of quickly producing pathologic section, the bubble dynamics in ultrasonic sonoporation is investigated by constructing a model of cavitated bubbles and altering the parameters, such as the ultrasonic signal frequency, acoustic pressure, bubbles' original radius and viscosity of the fluid. Numerical simulations indicate that radial vibration of cavitating bubble can keep on a steady process of expanding, shrinking, and vibrating in a given rang of frequencies, and one can find out the best original radius for obtaining the maximal cavitation. There exist a best cavitation regions which are determined by the parameters, i.e., the ultrasonic signal frequency, acoustic pressure, bubbles' original radius and viscosity of body fluid.