Open AccessMonte Carlo simulation of chromatin fiber conformation affected by ionic strength
Author(s) -
Guan Zhi-Qiang,
Xue Yan-Pin,
Hai Lin,
He Gui-Li,
ChenXu Wu
Publication year - 2006
Publication title -
wuli xuebao
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.199
H-Index - 47
ISSN - 1000-3290
DOI - 10.7498/aps.55.460
Subject(s) - monte carlo method , ionic bonding , sawtooth wave , chromatin , fiber , chemical physics , materials science , ion , ionic strength , statistical physics , computer science , chemistry , physics , composite material , dna , aqueous solution , telecommunications , biochemistry , statistics , mathematics , organic chemistry
In this paper, using Monte Carlo simulation, we obtain different structures of chromatin fibers with different ionic concentration. The result shows that as the ionic concentration is increased, the fiber undergoes a conformational change from sawtooth state to super-helix state. The structural parameters obtained by simulation agree well with the experimental results, indicating that our model is useful in explaining the conformational change of chromatin fibers in different ionic solutions.