Open AccessA STUDY FOR THE INFLUENCE OF RICINOLEIC ACID ON THE LIQUID CRYSTAL STRUCTURE IN THE MIXED PHOSPHOLIPID CHOLESTEROL LIPOSOMES BY MEANS OF SAXS AND 31P-NMR
Author(s) -
RunCang Sun,
Jing Zhang,
Dai Zheng-Hua,
Xu Feng-Xun,
Wang De-Hua
Publication year - 1994
Publication title -
wuli xuebao
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.199
H-Index - 47
ISSN - 1000-3290
DOI - 10.7498/aps.43.616
Subject(s) - small angle x ray scattering , polyvinylpyrrolidone , liposome , ricinoleic acid , phospholipid , materials science , phosphoric acid , chemical engineering , organic chemistry , crystallography , membrane , scattering , polymer chemistry , chemistry , optics , nanotechnology , castor oil , biochemistry , physics , engineering , metallurgy
This report presents the results on the investigation of the effect of ricionoleic acid on the structures of the liquid crystal state of mixed phospholipid-cholesterol liposomes by means of the Small Angle X-ray Scattering (SAXS) and 31P Nuclear Magnetism Resomance(31P-NMR). The study shows that the ricinoleic acid helps to stabilize the structure of the mixed phospholipid-cholesterol liposomes and that the polyphase liposome with ricinoleic acid prepared from phosphoric buffer solution containing polyvinylpyrrolidone (PVP) is in the cubic-hexagonal phase.