Open AccessAktivitas Penghentian Pendarahan Luar Ekstrak Etanol Daun Berenuk (Crescentia cujete L) Secara In-Vivo
Author(s) -
Anjar Mahardian Kusuma,
Adri Nurrakhmat Sulistyo,
Susanti Susanti,
Sabikis Sabikis
Publication year - 2014
Publication title -
pharmaceutical sciences and research
Language(s) - English
Resource type - Journals
eISSN - 2477-0612
pISSN - 2407-2354
DOI - 10.7454/psr.v1i2.3299
Subject(s) - traditional medicine , bacillus subtilis , biology , horticulture , botany , medicine , toxicology , bacteria , genetics
Crescentia cujete L. or better known as calabash is a plant that thrives in Indonesia. Calabash has a great potential as an herbal remedy, but there is only a few scientific researches conducted on this plant, one of which is antibacterial against Bacillus subtilis and Escerichia coli on 2006 by Susanti. The method of this research was an experimental activity assay of external bleeding cessation with 3 dose variations of calabash leaf extract (80%, 60%, and 40%) by counting the bleeding time at the base of mice tail. The result showed that all 3 dose variatons had better outcomes in external bleeding cessation activity than negative controls (p<0,05)