Open AccessTrack B Clinical Science
Author(s) -
jias
Publication year - 2012
Publication title -
journal of the international aids society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.724
H-Index - 62
ISSN - 1758-2652
DOI - 10.7448/ias.15.5.18439
Subject(s) - medicine , genotyping , immunology , tuberculosis , genotype , single nucleotide polymorphism , snp , tlr4 , immune system , innate immune system , cohort , virology , biology , gene , genetics , pathology
Toll‐like receptors (TLRs) are transmembrane receptors that activate cells of the innate immune systems upon recognition of pathogen‐associated molecular patterns. The TLR4 is an essential component of the innate immune response to various microorganisms. We investigated the impact of TLR4 polymorphism on development of opportunistic diseases in HIV‐infected patients.