IN-VITRO STUDIES SUGGEST PROBABLE MECHANISM OF EUCALYPTUS OIL FOR ANTI-INFLAMMATORY AND ANTI-ARTHRITIC ACTIVITY | Zendy

Habibur Rahman | Zendy; Chinna M Eswaraiah | Zendy; Kamala Vakati | Zendy; P Madhavi | Zendy

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IN-VITRO STUDIES SUGGEST PROBABLE MECHANISM OF EUCALYPTUS OIL FOR ANTI-INFLAMMATORY AND ANTI-ARTHRITIC ACTIVITY

Author(s) -

Habibur Rahman,

Chinna M Eswaraiah,

Kamala Vakati,

P Madhavi

Publication year - 2012

Publication title -

international journal of phytopharmacy

Language(s) - English

Resource type - Journals

ISSN - 2277-2928

DOI - 10.7439/ijpp.v2i3.507

Subject(s) - bovine serum albumin , in vitro , chemistry , aspirin , anti inflammatory , denaturation (fissile materials) , pharmacology , eucalyptus oil , chromatography , biochemistry , medicine , immunology , nuclear chemistry

The present study aimed to study in-vitro anti-inflammatory and anti-arthritic activity of Eucalyptus globules oil. Anti-inflammatory activity of Eucalyptus globules oil at 100, 250, 500 mcg/ml were studied using human red blood cell membrane (HRBC) stabilization method and anti-arthritic activity of same concentration using bovine serum albumin denaturation(BSA) method. The effect Diclofenec and Aspirin at concentration of 100, 200 mcg/ml were also assessed as standard drug. Results showed significant (53.48%, 63.73% and 70.66% at 100, 250 and 500 mcg/ml of EGO) protection of HRBC and significant inhibition (16.98%, 58.49%, 66.03% at 100, 250 and 500 mcg/ml of EGO) in BSA denaturation and which are comparable to standard drugs diclofenec and aspirin. This result suggests about their potential action as anti-inflammatory and ant-arthritic activity and sets a platform for therapeutic use.