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Evaluation and histopathological correlation of abnormal uterine bleeding in perimenopausal women
Author(s) -
Avantika Gupta,
Asmita Rathore,
Usha Manaktala,
Poonam Rudingwa
Publication year - 2013
Publication title -
international journal of biomedical and advance research
Language(s) - English
Resource type - Journals
eISSN - 2455-0558
pISSN - 2229-3809
DOI - 10.7439/ijbar.v4i8.258
Subject(s) - uterine bleeding , medicine , obstetrics , correlation , gynecology , mathematics , geometry

Objectives : To study the causes of abnormal uterine bleeding in perimenopausal women and to correlate their clinical evaluation with ultrasonographic and histopathological examination.

Method : This is a retrospective study of 100 perimenopausal women with complaint of abnormal bleeding in the age group ranging from 40 years till 1 year within the menopause, who underwent hysterectomy at Lok Nayak Hospital. The age, parity, menstrual complaints of these patients were noted & clinical diagnosis and ultrasonography were analysed. Finally, histopathology report of the hysterectomy specimen was correlated with the clinical profile of the patient and ultrasonographic findings.

Results : Maximum frequency of abnormal uterine bleeding was seen in the age group 40– 45 years. Most of the patients were para 3. Menorrhagia was the commonest complaint & fibroid uterus was responsible for abnormal uterine bleeding in 53% of women. Out of 42 women labelled clinically as dysfunctional uterine bleeding, 9 patients were diagnosed with fibroid uterus on ultrasound, 3 with malignancy, 1 with adenomyosis & in rest of the 30 patients, no organic cause was found. Out of these 30 patients, 6 patients were diagnosed to have adenomyosis on histopathology & in rest 24 patients, no gross pathology was detected. Suspected malignancy in all the 3 patients was confirmed on histopathology. Simple endometrial hyperplasia without atypia was present in 24% patients.

Conclusion : Clinical, radiological & pathological evaluation correlated well to diagnose fibroids, however clinically as well as ultrasound proved to be of little help in diagnosing adenomyosis.

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