Open AccessThe histopathological study of granulomatous diseases in various organ to find the exact etiology of granulomas
Author(s) -
Dr.Vaidehi Patel,
Dr.Jasmin H Jasani,
Dr.Rajol I Desai
Publication year - 2013
Publication title -
international journal of biomedical and advance research
Language(s) - English
Resource type - Journals
eISSN - 2455-0558
pISSN - 2229-3809
DOI - 10.7439/ijbar.v4i7.401
Subject(s) - etiology , stain , pathology , haematoxylin , staining , histopathology , granuloma , medicine , histopathological examination , h&e stain
This study was conducted to find out the etiology of all granulomatous lesions on Histo-pathology and Cytological studies. Our study was done at SBKS MI & RC, Piparia from January 2011 to July 2012. All the cases which were clinically diagnosed and suspected of granulomas, on haematoxylin and eosin stained sections were studied. Special stains like Ziehl Neelsen stain, PAS stain and Fite Faraco stain were done whenever required. The morphological features and special staining helped us to find the specific etiology of Granulomas in 123 cases whereas it could not be determined in 7 cases even after special stains. Thus we conclude that Cytological study of granulomatous lesions helped us to find the exact etiology of Granulomas in 81% of cases whereas Histopathological examination of granulomatous lesions helped us to find the exact etiology of Granulomas in 95 % of cases. The correlation of histo-pathology with PCR, serological tests and culture correlation would have helped to find the specific etiology in the remaining case