PREVALENCE AND ANTIMICROBIAL SUSCEPTIBILITY OF URINO PATHOGEN AMONG PATIENTS IN A TERTIARY HEALTH INSTITUTION IN ADO EKITI, NIGERIA | Zendy

Y Daniyan | Zendy; Maria Osintseva | Zendy

Open Access

PREVALENCE AND ANTIMICROBIAL SUSCEPTIBILITY OF URINO PATHOGEN AMONG PATIENTS IN A TERTIARY HEALTH INSTITUTION IN ADO EKITI, NIGERIA

Author(s) -

Y Daniyan,

Maria Osintseva

Publication year - 2013

Publication title -

international journal of biomedical and advance research

Language(s) - English

Resource type - Journals

eISSN - 2455-0558

pISSN - 2229-3809

DOI - 10.7439/ijbar.v4i3.841

Subject(s) - antimicrobial , pathogen , institution , tertiary institution , medicine , traditional medicine , family medicine , biology , microbiology and biotechnology , immunology , political science , medical education , law

Objectives: This study was carried out to determine the prevalence and antibiotic susceptibility of bacteria associated with urinary tract infection (UTI) of patient in one of the tertiary health institution, Nigeria. Method: Clean-catch midstream urine was collected from 130 patients (57 males and 73 females) and culture on CLED agar plates. Isolates were identified and antibiotic susceptibility testing was performed. Results: The prevalence of urinary tract infection was significantly higher in females (68.5%) compared to males (45.6%). Seventy six (58.46%) were urine culture positive for microbial pathogens with 82 microbial isolates. In general 55 (67.07%) isolates were gram negative and 27 (32.93%) isolates were gram positive. Escherichia coli 26 (31.7%) has the highest percentage follow by Staphylococcus aureus 18(21.9%) and Klebsiella spp 10 (12.2%). The in vitro antibiotic susceptibility pattern of the isolates show high resistance to common antibiotic used. Nitrofurantoin has the highest antibiotic activity with total average percentage of 63.9% in gram negative isolates followed by Ofloxacin 34.4%, while total average percentage of 38.2% isolates were susceptible to Chloramphenical and 22.5% to Tetracycline, but highest resistance were shown in Amoxicillin Cloxacillin, Augumentin, Cotrimoxazole and Gentamicin. Conclusion: A 58.46% prevalence of UTIs was found. This problem remarks significance of performing antimicrobial susceptibility testing before empiric antibiotic therapy.