Open AccessUse of recombinant activated factor VII in Primary Postpartum Hemorrhage – its necessity in supply to the peripheries
Author(s) -
Madhusudan Dey,
Rakesh Kumar,
Nagaraja Narayan
Publication year - 2013
Publication title -
international journal of biomedical and advance research
Language(s) - English
Resource type - Journals
eISSN - 2455-0558
pISSN - 2229-3809
DOI - 10.7439/ijbar.v4i1.933
Subject(s) - recombinant dna , primary (astronomy) , medicine , factor (programming language) , obstetrics , chemistry , computer science , biochemistry , physics , astronomy , gene , programming language
Postpartum hemorrhage (PPH) is a life-threatening emergency in obstetrics. In some critical cases, hemostasis is hard to achieve even after a hysterectomy has been performed. Early, effective and preferably non invasive treatments that can reduce maternal mortality and morbidity are therefore essential. Recombinant activated factor seven (rFVIIa) has been reported as a promising adjuvant therapy for obstetric hemorrhage, although it remains unlicensed for this indication. We are presenting four cases of primary PPH successfully managed using rFVIIa.