Open AccessImaging of Juvenile onset Leigh Syndrome: A Case Report and Short Review of Literature
Author(s) -
Varuna Gupta
Publication year - 2012
Publication title -
international journal of biomedical and advance research
Language(s) - English
Resource type - Journals
eISSN - 2455-0558
pISSN - 2229-3809
DOI - 10.7439/ijbar.v3i7.592
Subject(s) - neuroimaging , medicine , disease , leigh disease , juvenile , rare disease , pediatrics , incidence (geometry) , polyneuropathy , pathology , psychiatry , biology , genetics , biochemistry , physics , optics , mitochondrial dna , gene
Leigh's disease is a rare entity affecting the central nervous system generally of infants, incidence being 1 in 40,000. Rarely, it occurs in teenagers and adults. The diagnosis is difficult and still continues to challenge the clinicians on the basis of history; hence the role of imaging is very crucial. The neuropathy encountered in the disease is commonly associated with features of demyelination, presenting rarely in acute form. A case of Juvenile Leigh Disease is reported here presenting with an acute polyneuropathy. Neuroimaging confirmed it to be a case of Leigh disease.