Open AccessIntroduction: Midline laprotomy is the most common technique of abdominal incisions in both emergency and elective settings because it is simple, provides adequate exposure to all four quadrants, affords quick exposure with minimal blood loss. There have been very few studies comparing the continuous method of closure with interrupted using absorbable and non absorbable sutures in patients with peritonitis with delayed primary closure of skin. Hence this study has been taken up. Materials and Methods: 80 patients with age group 18 yrs -70 years admitted in all surgical units of Basaveshwar Teaching and General Hospital were included. The patients were divided into four groups. Regular follow up of patients was done on 2, 4,6,12 weeks after surgery in OPD. The patients were examined for wound infection and suture sinus. Results and Discussion: No statistical difference in either technique was observed in terms of wound infection, wound dehiscence, incisional hernia formation and total duration of hospital stay. Continuous suturing was found to be easier, faster and economical and associated with less suture sinus formation. Conclusion: Continuous polydioxanone is the preferred material and method of closure for abdominal fascia closure for acute peritonitis in combination with delayed primary closure of skin.