Open AccessANTIIMPLANTATION ACTIVITY OF THE METHANOLIC EXTRACT OF CORDIA DICHOTOMA LAM. BARK IN RATS
Author(s) -
Parimal Katolkar,
B. E. Wanjari,
Tulsidas Nimbekar,
Nandkishor J. Duragkar
Publication year - 2012
Publication title -
international journal of biomedical and advance research
Language(s) - English
Resource type - Journals
eISSN - 2455-0558
pISSN - 2229-3809
DOI - 10.7439/ijbar.v3i3.315
Subject(s) - traditional medicine , bark (sound) , medicine , biology , ecology
In the present study, antiimplantation activity of methanolic extract of Cordia dichotoma Lam. bark was evaluated. The methanolic extract of bark of Cordia dichotoma showed significant antiimplantation activity. Pretreatment with methanolic extract showed significant inhibition of number of implant site at a dose of 100-mg/kg-body weight. There was no change in ovulation; hence the antiimplantation activity observed in the present study with Cordia dichotoma bark can be attributed largely to its inhibition of number of implants. However, an investigation of  the antiimplantation activity showed  no increase in body weight or uterine content of blood glucose, cholesterol and triglyceride levels when compared with control group.