Open AccessHYPOLIPIDEMIC ACTIVITY OF ETHANOLIC EXTRACT OF DAUCUS CAROTA SEEDS IN NORMAL RATS
Author(s) -
Kamlesh Singh,
Hemant Dhongade,
Nisha Singh,
Pranita Kashyap
Publication year - 2011
Publication title -
international journal of biomedical and advance research
Language(s) - English
Resource type - Journals
eISSN - 2455-0558
pISSN - 2229-3809
DOI - 10.7439/ijbar.v1i3.4
Subject(s) - daucus carota , traditional medicine , chemistry , horticulture , biology , food science , botany , medicine
Objective: Hypolipidemic activity of ethanolic extract of Daucus carota seeds in Normal rats. Method: Rats were divided in to 4 groups. First control group, treated with vehicle only for 7 days. Second group was standard, treated with lovastatin (7.2mg/kg) for 7 days. Third and fourth group were test, treated with Daucus carota seeds extract (200mg/kg and 400mg/kg) for 7 days. 8th day blood sample was collected by retro orbital route and lipid profiles were estimated in serum. Result and Conclusions: Standard and test (400mg/kg DCSE) groups were showed significant (P <0.001) reduction in the total cholesterol, triglyceride HDL and VLDL as compared control group. Test group (200mg/kg) was showed significant (P <0.05) reduction as compared control group. The antioxidant potential of Daucus carota seeds has contributed to the reduction of oxidative stress and Lipid levels in experimental rats