Open AccessHerbal derived nanomedicines against for some human pathogens
Author(s) -
R. Amirthavarshini,
A. Vinoth Kanna,
Sarmad Moin,
T. Uma sankari
Publication year - 2017
Publication title -
international journal of advances in scientific research
Language(s) - English
Resource type - Journals
ISSN - 2395-3616
DOI - 10.7439/ijasr.v3i1.3888
Subject(s) - micrococcus luteus , dynamic light scattering , chemistry , microbiology and biotechnology , scanning electron microscope , antimicrobial , bacteria , silver nanoparticle , nuclear chemistry , nanoparticle , food science , materials science , nanotechnology , biology , escherichia coli , biochemistry , genetics , composite material , gene
The aim of this study was to achieve the silver nanocrystals for therapeutic values. The Aristolochia bractiata leaves extract as a reducing substance for the biosynthesis of silver nanoparticles. UV-Vis spectra analysis, Dynamic Light Scattering Particle size analyzer, X-ray Diffraction method and Scanning electron microscopy (SEM) with X-ray spectroscopy (EDS) have been employed to characterize and confirmed the nanocrystal formation. In antimicrobial activity, the silver nanoparticles were most against some human pathogens. In bacteria, the test sample was most effective against Salmonella typhimurium NCIM 2501 (B5) while smaller effect was noticed from Micrococcus luteus NCIM 2871 (B4). In fungi, which was effective against Trichophyton rubrum MTCC 3272 (F4) whereas smaller effect was observed in Cryptococcus sp. MTCC 7076 (F2). All the microbial strains depict higher sensitivity to the higher concentration (30?L) for the test sample when compared to the positive control except few bacterial strains.