Cases in Precision Medicine: The Role of Pharmacogenetics in Precision Prescribing | Zendy

Bohan Lin | Zendy; Wendy K. Chung | Zendy

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Cases in Precision Medicine: The Role of Pharmacogenetics in Precision Prescribing

Author(s) -

Bohan Lin,

Wendy K. Chung

Publication year - 2019

Publication title -

annals of internal medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.839

H-Index - 390

eISSN - 1539-3704

pISSN - 0003-4819

DOI - 10.7326/m18-2357

Subject(s) - medicine , pharmacogenetics , context (archaeology) , precision medicine , warfarin , intensive care medicine , adverse effect , personalized medicine , drug , affect (linguistics) , pharmacology , medical physics , bioinformatics , pathology , paleontology , biochemistry , chemistry , linguistics , philosophy , biology , genotype , gene , atrial fibrillation

Pharmacogenetics may help physicians deliver individualized treatments based on how a person's genes affect a drug's effects and metabolism. This information can help prevent adverse events or improve drug efficacy by enabling the physician to optimize dosage or to avoid a medication with adverse reactions and to prescribe an alternative therapy. This article discusses the current clinical utility of pharmacogenetic testing in the context of a patient who requires anticoagulation with warfarin.

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