Open AccessMeta-Analysis of the Association between H63D and C282Y Polymorphisms in HFE and Cancer Risk
Author(s) -
Meng Zhang,
Hu Xiong,
Fang Lü,
Wei Lü,
Xun Wu,
Yongqiang Wang,
Zhiming Cai,
Song Wu
Publication year - 2015
Publication title -
asian pacific journal of cancer prevention
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 75
eISSN - 2476-762X
pISSN - 1513-7368
DOI - 10.7314/apjcp.2015.16.11.4633
Subject(s) - medicine , meta analysis , hepatocellular carcinoma , case control study , allele , oncology , gastroenterology , web of science , genetics , biology , gene
Previous studies suggested that the H63D and C282Y polymorphisms in the HFE genes were susceptible to many cancer types, nevertheless, the present results were inconclusive. Thus, the present study was aimed to evaluate the association between the HFE polymorphisms (H63D and C282Y) and cancer risk via meta-analysis.