Open AccessLack of Prognostic Significance of SOCS-1 Expression in Colorectal Adenocarcinomas
Author(s) -
Talat Ayyıldız,
Enver Dolar,
Şaduman Balaban Adım,
Ahmet Tarık Eminler,
Ömer Yerci
Publication year - 2014
Publication title -
asian pacific journal of cancer prevention
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 75
eISSN - 2476-762X
pISSN - 1513-7368
DOI - 10.7314/apjcp.2014.15.19.8469
Subject(s) - colorectal cancer , immunohistochemistry , suppressor , cancer research , clinical significance , tumor suppressor gene , medicine , deleted in colorectal cancer , oncology , cancer , carcinogenesis
Recent studies have indicated that down-regulation of the suppressor of cytokine signaling-1 (SOCS-1) gene results in tumor formation and that SOCS-1 acts as a tumor suppressor gene. SOCS-1 has been also suggested to function as a tumor suppressor with colorectal cancer.