Association Between XRCC5, 6 and 7 Gene Polymorphisms and the Risk of Breast Cancer: A HuGE Review and Meta-analysis | Zendy

Liping Zhou | Zendy; Hong Luan | Zendy; Xi-Hua Dong | Zendy; Guojiang Jin | Zendy; Dongliang Man | Zendy; Hong Shang | Zendy

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Association Between XRCC5, 6 and 7 Gene Polymorphisms and the Risk of Breast Cancer: A HuGE Review and Meta-analysis

Author(s) -

Liping Zhou,

Hong Luan,

Xi-Hua Dong,

Guojiang Jin,

Dongliang Man,

Hong Shang

Publication year - 2012

Publication title -

asian pacific journal of cancer prevention

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.512

H-Index - 75

eISSN - 2476-762X

pISSN - 1513-7368

DOI - 10.7314/apjcp.2012.13.8.3637

Subject(s) - breast cancer , cochrane library , meta analysis , odds ratio , web of science , oncology , bioinformatics , medicine , gene , cancer , biology , genetics

Non-homologous end joining (NHEJ) is a pathway for repairing DNA double-strand breaks. Recent publications indicated that XRCC5, XRCC6 and XRCC7 genes may participate in the pathogenesis of breast cancer. The aim of this Human Genome Epidemiology (HuGE) review and meta-analysis was to investigate associations between XRCC5, XRCC6 and XRCC7 genetic polymorphisms in the NHEJ pathway and breast cancer risk.

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