Open Access3R Variant of Thymidylate Synthase 5'-untranslated Enhanced Region Contributes to Colorectal Cancer Risk: A Meta-analysis
Author(s) -
Min Lü,
Luhaoran Sun,
Jing Yang,
Yue-Yao Li
Publication year - 2012
Publication title -
asian pacific journal of cancer prevention
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 75
eISSN - 2476-762X
pISSN - 1513-7368
DOI - 10.7314/apjcp.2012.13.6.2605
Subject(s) - thymidylate synthase , meta analysis , odds ratio , colorectal cancer , medicine , confidence interval , oncology , population , genotype , subgroup analysis , case control study , gastroenterology , biology , bioinformatics , cancer , genetics , gene , fluorouracil , environmental health
Studies investigating the association of 2R/3R polymorphism in the thymidylate synthase 5'-untranslated enhanced region (TSER) and colorectal cancer (CRC) risk have reported conflicting results. Thus, a meta-analysis was performed to summarize the data on the potential association.