MLH1 Polymorphisms and Cancer risk: a Meta-analysis Based on 33 Case-control Studies | Zendy

Jiali Xu | Zendy; Zhiqiang Yin | Zendy; Mingde Huang | Zendy; Xiefeng Wang | Zendy; Wen Gao | Zendy; Lingxiang Liu | Zendy; Rongsheng Wang | Zendy; Pu-Wen Huang | Zendy; Yongmei Yin | Zendy; Ping Liu | Zendy; Yongqian Shu | Zendy

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MLH1 Polymorphisms and Cancer risk: a Meta-analysis Based on 33 Case-control Studies

Author(s) -

Jiali Xu,

Zhiqiang Yin,

Mingde Huang,

Xiefeng Wang,

Wen Gao,

Lingxiang Liu,

Rongsheng Wang,

Pu-Wen Huang,

Yongmei Yin,

Ping Liu,

Yongqian Shu

Publication year - 2012

Publication title -

asian pacific journal of cancer prevention

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.512

H-Index - 75

eISSN - 2476-762X

pISSN - 1513-7368

DOI - 10.7314/apjcp.2012.13.3.901

Subject(s) - mlh1 , meta analysis , case control study , medicine , cancer , oncology , colorectal cancer , dna mismatch repair

Cumulative evidence suggests that MLH1, the key component in the mismatch pathway, plays an important role in human cancers. Two potential functional polymorphisms (-93G>A and I219V) of MLH1 have been implicated in cancer risk. The aim of this meta-analysis was to summarize the evidence for associations.

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