Open AccessDIFFERENT TYPES OF COLORECTAL CARCINOMA CHARACTERIZATION USING STAINED AND NON STAINED PLATES BY OPTO-MAGNETIC SPECTROSCOPY
Author(s) -
Aleksandra Dragičević,
Zoran Krivokapić,
V Marković,
Goraikolić,
Lidija Matija
Publication year - 2014
Publication title -
contemporary materials
Language(s) - English
Resource type - Journals
eISSN - 1986-8677
pISSN - 1986-8669
DOI - 10.7251/comen1401161d
Subject(s) - colorectal cancer , characterization (materials science) , cancer , staining , in vivo , carcinoma , spectroscopy , pathology , materials science , medicine , biomedical engineering , nanotechnology , biology , physics , microbiology and biotechnology , quantum mechanics
According to the World Health Organization cancer is the leading cause of death worldwide and on the third place is the most common and dangerous colorectal cancer with the rate of 17.3/100,000 people. Therefore, it is necessary to find effective solutions to improve the quality and speed of diagnostic tools so that they can respond to the challenges of prevention strategies which are an integral part of the rapid diagnosis of a large number of patients. The objectives of the research conducted in this study (in vitro) are: (1) examining the possibilities of application of opto-magnetic imaging spectroscopy for characterization between different types of colon cancer, stained and non-stained plates, (2) method validation, (3) parameters determination for research in in vivo conditions, and (4) application in clinical trial to increase the efficiency and give more reliable diagnosis. In this paper we present Opto-magnetic imaging spectroscopy (OMIS) as a novel optical method for differentiation of different types of colon cancer, significant similarity between stained and non-stained plates based on light-tissue interaction. Results have showed that OMIS can make a difference between colorectal carcinoma and other types of colon cancer, as well as prove that plates staining can be avoided.