Efficacy of excimer light therapy for treatment of localized, progressive vitiligo

Vitiligo is an acquired, circumscribed, depigmented macules due to loss of functional melanocytes. Excimer light cause immunosuppression as well as stimulation of follicular melanocytes.\ud\udMaterials and Methods: After taking consent, the dose of the therapy was arbitrarily started at 100 mj/cm2, given twice a week, with incremental dose of 100 j/cm2 every sitting. If erythema (or blister, if any) persists for more than 2 days, the dose was skipped until erythema (or blister) subsided. Then, the previous safe dose was continued. A total of 16 sittings was given. Photographs were taken pretreatment, after 2 months and after 4 months and were assessed by two independent doctors who were not involved in the study.\ud\udResults: Among 25 patients, 16 patients (64%) achieved good results and 3 patients (12%) achieved excellent result.\ud\udConclusion: Excimer light therapy is a good option for treatment of localized vitiligo. However, those lesions on the lips and acral areas responded very poorly