Open AccessGranulosa cells tumor in mules
Author(s) -
S. M. González,
Camila Bizarro da Silva,
Fernanda Zandonadi Machado,
Gustavo Romero Gonçalves,
Kátia Cristina Silva-Santos,
Marcelo Marcondes Seneda
Publication year - 2015
Publication title -
revista acadêmica ciência animal
Language(s) - English
Resource type - Journals
ISSN - 2596-2868
DOI - 10.7213/academica.13.fc.ao09
Subject(s) - histology , ovary , biology , granulosa cell , seasonal breeder , antral follicle , medicine , anatomy , pathology , gynecology , endocrinology , zoology
Due to the current understanding of infertility and absence of ovarian activity in the female mule, scientificmaterial regarding their reproductive tract is lacking. Information regarding evaluation of the reproductivesystem, as well as diagnoses of ovarian neoplasms, is scarce for female mules. The purpose of this paperis to report the first case of granulosa cell tumor (GCT) in a female mule, characterized through histology,which suggests evidence of cyclicity. During the breeding season, within the Southern hemisphere, mules’ovaries were obtained from slaughterhouses. Notably, a pair ovarian rated was remarkable in size (16.5cm in diameter), weight (1.92 kg) as well as number of antral follicles. On sagittal section, the tissue wastrabecular and fluid filled. Histology revealed irregular cyst formations full of amphophilic fluid ranging incolor from pinkish to purple. The granulosa cells showed up in abnormal histology, featuring a granulosacell tumor. The contralateral ovary was evaluated, demonstrating anatomy, weight and granulosa cellsfrom normal. Therefore, we have described the first granulosa cells tumor report in a mule via gross andhistological features, which suggests evidence of cyclicity in female mules.