New therapeutic options in psoriasis

The biological therapy of moderate-to-severe psoriasis has a history of almost two decades. During this period our knowledge of the pathomechanism of the disease has become more accurate, leading to the development of more and more targeted therapies. Increased efficacy through more specific inhibition is accompanied by less adverse events. In this article, the authors summarize the current possibilities for the modern treatment of psoriasis and the key clinical insights into these options. They discuss the future therapeutic directions and new agents.