Open AccessCase series of skin symptoms possibly related to SARS-CoV-2 infection admitted to Heim Pál Children’s Hospital and review of the literature
Author(s) -
V. Klara,
G. A. Izabella,
S. Andras,
P. Borbala,
Safak Reka,
Z. Borbala,
Manca Anna Rita,
S. Z. Zsofia
Publication year - 2021
Publication title -
bőrgyógyászati és venerológiai szemle
Language(s) - English
Resource type - Journals
eISSN - 2064-261X
pISSN - 0006-7768
DOI - 10.7188/bvsz.2021.97.1.5
Subject(s) - medicine , serology , kawasaki disease , covid-19 , antibody , pediatrics , titer , disease , virus , antibody titer , dermatology , immunology , infectious disease (medical specialty) , artery
The COVID-19 pandemic, which started in China in December2019, is caused by the SARS-CoV-2 virus. In addition to severe, even life-threatening respiratory symptoms caused by the SARS-CoV-2 virus, a number of systemic and atypical skin symptoms have developed in young patients. This article presents cases of skin symptoms possibly provoked by SARS-CoV-2 virus attended to Pál Heim Children’s Hospital from 15 November to 31 December 2020. Four chilblain-like acral lesions and one case of multiple organ failure similar to Kawasaki disease are presented. The SARS-COV-2 PCR test was negative in all cases, however, high antibody titer was found by serologic testing for antibodies in two cases. In another case, the frst antibody test found doubtful positivity, however, high antibody levels were confrmed one month later. Based on our fndings, it is presumed, that pernio-like symptoms and multiple organ failure similar to Kawasaki disease could be late symptoms of COVID-19. The authors also summarize the most common skin symptoms associated with SARS-CoV-2 infection in children, highlighting the diferent pediatric aspects from adult cases.