Alteration among the patch test allergens in the environmental standard baseline series of the Allergology Laboratory of the National Dermatological and Venereological Institute and the Department of Dermatology, Venereology and Dermatooncology of Semmelweis University

The patch test has been the standard diagnostic tool of verifying contact hypersensitivity for decades. The test’s methodological elements and the tested allergen groups are the achievements of a dynamically changing process of the 20th century. Most commonly, the environmental standard baseline series is used in everyday clinical practice. Te frst environmental series in Hungary, which was recommended for national use, was created in the Allergology Laboratory of the National Dermatological and Venereological Institute in the 1970 years. It consisted of 21 allergens. Afer the Institute’s closure, the Semmelweis University, Department of Dermatology, Venereology and Dermatooncology continued to perform the patch testing. Te number of the baseline series members became more than doubled by now. This review aims to summarise the alterations in the environmental standard baseline series of the Allergology Laboratory of the National Dermatological and Venereological Institute and the Department of Dermatology, Venereology and Dermatooncology of the Semmelweis University and the sensitisation frequencies registered from 1976 to 2016 per 10 year periods.