A case of beta-thalassaemia major resistant to standard treatment | Zendy

Nicoletta Masera | Zendy; Valentina Decimi | Zendy; Luisa Tavecchia | Zendy; Marietta Capra | Zendy; Giovanni Cazzaniga | Zendy; Andrea Biondi | Zendy; Giuseppe Masera | Zendy

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A case of beta-thalassaemia major resistant to standard treatment

Author(s) -

Nicoletta Masera,

Valentina Decimi,

Luisa Tavecchia,

Marietta Capra,

Giovanni Cazzaniga,

Andrea Biondi,

Giuseppe Masera

Publication year - 2010

Publication title -

clinical management issues

Language(s) - English

Resource type - Journals

eISSN - 2283-3137

pISSN - 1973-4832

DOI - 10.7175/cmi.v4i2.531

Subject(s) - medicine , thalidomide , pediatrics , beta (programming language) , computer science , multiple myeloma , programming language

We report the case of a 22-year-old woman from Albania, with thalassaemia major, in severe clinical condition who could no longer be transfused due to the occurrence of severe, acute, post-transfusional reactions. After 10 years of treatment, she failed to respond to hydroxyurea. When she received thalidomide, haemoglobin levels increased from 3.7 g/dl to 9 g/dl. Since then, at 22 months of follow-up, the therapy is still effective and well tolerated. The case gives the opportunity to describe the clinical use of thalidomide, and its potential in the management of beta-thalassaemia

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