A severe infective endocarditis successfully treated with linezolid | Zendy

Graziano Antonio Minafra | Zendy; Donatella Cibelli | Zendy; M. Pipino | Zendy; Vincenzo Dargenio | Zendy; Francesco Ventrella | Zendy

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A severe infective endocarditis successfully treated with linezolid

Author(s) -

Graziano Antonio Minafra,

Donatella Cibelli,

M. Pipino,

Vincenzo Dargenio,

Francesco Ventrella

Publication year - 2010

Publication title -

clinical management issues

Language(s) - English

Resource type - Journals

eISSN - 2283-3137

pISSN - 1973-4832

DOI - 10.7175/cmi.v4i1.538

Subject(s) - linezolid , medicine , endocarditis , infective endocarditis , pneumonia , antibiotics , surgery , streptococcus bovis , microbiology and biotechnology , staphylococcus aureus , vancomycin , bacteria , rumen , chemistry , food science , biology , fermentation , genetics

Despite significant improvements in surgical and medical therapy, prosthetic valve endocarditis (PVE) is a diagnostic and therapeutic challenge and is often associated with a severe prognosis. We report a case of a 59-year-old woman, with PVE and bacterial endocarditis (Streptococcus bovis) successfully treated with linezolid. Linezolid is a bacteriostatic oxazolidinone antibiotic that has been proven to be effective for the treatment of patients with pneumonia, skin and soft tissue infections, and infections due to Gram-positive cocci. Linezolid is not yet recognised as a standard therapy for infective endocarditis, but its use becomes a necessity when infection is due to multidrug-resistant microorganisms

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