Changes in the intralinear level of hybrid dys-genesis manifestation in Drosophila melanogaster in crosses with individuals with tetracycline suppressed internal microflora

Aim. To assess the frequency of hybrid dysgenesis in the offspring of reciprocal crosses of individuals of the Oregon-R line, with individuals of the same line, from the organism of which Wolbachia pipientis was eliminated. Methods. The line of Drosophila melanogaster Oregon R (Cambridge), in the genome of which there are MGE hobo, was investiga-ted. This line is infected with wolbachia of the wMel strain. Removal of Wolbachia from the body was implemented using antibiotic tetracycline. The study used the fifth of the generations obtained on a normal handling medium after the removal of Wolbachia. The level of hybrid dysgenesis was studied by the method of extracting gonad flies and assessing their condition. Results. In the progeny from experimental crossing of females from which Wolbachia was eli-minated, with males of the control line, the proportion of females with fully reduced gonads is significantly higher than in the offspring of reciprocal crossing. Conclusions. The results obtained may be a sign of the action of the system of specific interactions of Wolbachia pipientis and Drosophila’s MGE. Keywords: mobile genetic elements, hybrid dysgenesis, Drosophila melanogaster, Wolbachia pipientis.