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Evaluation of the antimicrobial and resistance-modulating activities of extracts and fractions of Piper mollicomum (Piperaceae)
Author(s) -
Ana Raquel Pereira da Silva,
Micheline de Azevedo Lima,
Jacqueline Cosmo Andrade,
Celestina Elba Sobral de Souza,
Maria do Socorro Costa,
Maria Audilene de Freitas,
Henrique Douglas Melo Coutinho
Publication year - 2020
Publication title -
anales de biología
Language(s) - Spanish
Resource type - Journals
eISSN - 1989-2128
pISSN - 1138-3399
DOI - 10.6018/analesbio.42.17
Subject(s) - piperaceae , antimicrobial , piper , traditional medicine , biology , multiple drug resistance , antibiotic resistance , antibiotics , microbiology and biotechnology , medicine
Este estudio tuvo como objetivo evaluar las actividades antimicrobianas de diferentes extractos de Piper mollicomum Kunth ex Steud. contra cepas estándar y resistentes a múltiples fármacos de bacterias y hongos, así como analizar su potencial para modular la resistencia a los antimicrobianos. Los datos obtenidos en este trabajo demostraron una actividad potenciadora de antibióticos prometedora por parte de P. mollicomum, alentando el desarrollo de nuevas investigaciones para caracterizar las propiedades toxicológicas y farmacológicas de los extractos y compuestos aislados de esta especie, que pueden contribuir al desarrollo de nuevos agentes terapéuticos para combatir la resistencia a los antimicrobianos. This study aimed to evaluate the antimicrobial activities of different extracts of Piper mollicomum Kunth ex Steud. against standard and multidrug resistant strains of bacteria and fungi, as well as to analyze their potential to modulate antimicrobial resistance. The data obtained in this work demonstrated promising antibiotic-enhancing activity by P. mollicomum, encouraging the development of further research to characterize the toxicological and pharmacological properties of the extracts and isolated compounds of this species, which may contribute to the development of new therapeutic agents to combat antibacterial resistance.

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