Open AccessInfluence of the Preparation "Nicavet-1000" on a Morphofunctional Condition of some Organs of Rats at Experimental Aluminium Intoxication
Author(s) -
David А. Areshidze,
Lyudmila Timchenko,
Igor Rzhepakovsky,
Maria Kozlova,
Iaroslavna A. Kusnetsova,
Ivan A. Syomin
Publication year - 2017
Publication title -
journal of pharmacy and nutrition sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.141
H-Index - 10
ISSN - 1927-5951
DOI - 10.6000/1927-5951.2017.07.04.5
Subject(s) - erythropoiesis , bone tissue , hematocrit , chemistry , aluminium chloride , normalization (sociology) , aluminium , chloride , medicine , pathological , endocrinology , pathology , anemia , organic chemistry , sociology , anthropology
During the conducted research, it is established that aluminium chloride intoxication leads to the considerable changes of composition of red blood, development of a hypercalcemia and change of a bone structure of animals. A number of significant morphofunctional changes in the hippocampus of the examined animals are also noted. The use of the tissue preparation "Nicavet-1000" leads to the normalization of both hematocrit and other parameters of red blood, as well as to the intensification of erythropoiesis. Use of the preparation "Nicavet-1000", judging from the results of research, prevents pathological changes in a bone tissue, caused by aluminium chloride. "Nicavet-1000" leads to the expressed normalization of both the morphological, and micromorphometric parameters characterizing a hippocampus of rats.