Open AccessUsing miRNA‐mRNA Interaction Analysis to Link Biologically Relevant miRNAs to Stem Cell Identity Testing for Next‐Generation Culturing Development
Author(s) -
Crabbé Marian A.E.,
Gijbels Kristel,
Visser Aline,
Craeye David,
Walbers Sara,
Pinxteren Jef,
Deans Robert J.,
Annaert Wim,
Vaes Bart L.T.
Publication year - 2016
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2015-0154
Subject(s) - microrna , stem cell , computational biology , biology , microbiology and biotechnology , genetics , gene
microRNA (miRNA) markers differentially expressed under nonclinical multipotent adult progenitor cell and mesenchymal stem cell culturing conditions were found to regulate important stem cell features, such as proliferation and differentiation. The identified biologically relevant miRNA markers can be used to monitor stem cell stability when implementing variations in culturing procedures.