Open AccessGeneration of Functional Human Cardiac Progenitor Cells by High‐Efficiency Protein Transduction
Author(s) -
Li Xiao-Hong,
Li Qianqian,
Jiang Lin,
Deng Chunyu,
Liu Zaiyi,
Fu Yongheng,
Zhang Mengzhen,
Tan Honghong,
Feng Yuliang,
Shan Zhixin,
Wang Jianjun,
Yu Xi-Yong
Publication year - 2015
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2015-0136
Subject(s) - reprogramming , microbiology and biotechnology , biology , induced pluripotent stem cell , progenitor cell , mef2c , stem cell , cellular differentiation , somatic cell , histone , cell , embryonic stem cell , genetics , gene expression , gene
Protein‐induced cardiac progenitor cells (CPCs) that are directly reprogrammed in vitro might be applicable for replacing dead heart muscle after myocardial infarction. The use of undifferentiated CPCs as building blocks to grow specific tissue types in vivo is of great interest for regenerating the myocardium.