Open AccessOsteogenic Potential of Mouse Periosteum‐Derived Cells Sorted for CD90 In Vitro and In Vivo
Author(s) -
Kim You-Kyoung,
Nakata Hidemi,
Yamamoto Maiko,
Miyasaka Munemitsu,
Kasugai Shohei,
Kuroda Shinji
Publication year - 2016
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2015-0013
Subject(s) - periosteum , cd90 , mesenchymal stem cell , microbiology and biotechnology , regeneration (biology) , stem cell , in vivo , chemistry , biology , anatomy , cd34
The periosteum is considered a good source of osteogenic precursor cells for new bone formation. Three‐dimensional cell migration with atelocollagen and gelatin media was used; both were effective for promoting proliferation of periosteum‐derived cells. Periosteum‐derived cells sorted with CD90 showed higher proliferative capacity and osteogenic potential than unsorted periosteum‐derived cells. Thus, periosteum‐derived cells sorted with CD90 are expected to be a good source for bone regeneration.