The Lymph Node as a New Site for Kidney Organogenesis | Zendy

Francipane Maria Giovanna | Zendy; Lagasse Eric | Zendy

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The Lymph Node as a New Site for Kidney Organogenesis

Author(s) -

Francipane Maria Giovanna,

Lagasse Eric

Publication year - 2015

Publication title -

stem cells translational medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.781

H-Index - 71

eISSN - 2157-6580

pISSN - 2157-6564

DOI - 10.5966/sctm.2014-0208

Subject(s) - organogenesis , lymph node , biology , kidney development , kidney , computational biology , medicine , bioinformatics , pathology , genetics , embryonic stem cell , gene

This study investigated whether the lymph node (LN) could support kidney organogenesis from mouse renal embryonic tissue. Findings indicate that the LN might be exploited as an in vivo platform for kidney development studies, as well as in vivo validation of the differentiation potential of candidate stem cells in regenerative nephrology. The LN might also provide an exclusive site for kidney organogenesis for therapeutic purposes.

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