Open AccessIn Vitro Cell Motility as a Potential Mesenchymal Stem Cell Marker for Multipotency
Author(s) -
Bertolo Alessandro,
Gemperli Armin,
Gruber Marco,
Gantenbein Benjamin,
Baur Martin,
Pötzel Tobias,
Stoyanov Jivko
Publication year - 2015
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2014-0156
Subject(s) - mesenchymal stem cell , stem cell , motility , population , microbiology and biotechnology , biology , cell , in vitro , bone marrow , cellular differentiation , immunology , medicine , genetics , environmental health , gene
Life imaging as a tool to characterize populations of human mesenchymal stem cells (MSCs) was evaluated. Bone marrow MSCs were evaluated for their in vitro motility. The distances were correlated to the adipogenic, chondrogenic, and osteogenic differentiation potentials and senescence levels and cell size. In vitro cell motility might be a useful tool to quickly characterize and distinguish the MSC population's differentiation potential before additional use.