Open AccessXiphoid Process‐Derived Chondrocytes: A Novel Cell Source for Elastic Cartilage Regeneration
Author(s) -
Nam Seungwoo,
Cho Wheemoon,
Cho Hyunji,
Lee Jungsun,
Lee EunAh,
Son Youngsook
Publication year - 2014
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2014-0070
Subject(s) - cartilage , chondrogenesis , regeneration (biology) , chondrocyte , hyaline cartilage , microbiology and biotechnology , mesenchymal stem cell , transplantation , progenitor cell , tissue engineering , cellular differentiation , anatomy , biology , chemistry , biomedical engineering , stem cell , pathology , articular cartilage , medicine , osteoarthritis , surgery , biochemistry , alternative medicine , gene
Reconstruction of elastic cartilage requires a source of chondrocytes that display a reliable differentiation tendency. The authors found that xiphoid process cartilage, the only elastic cartilage tissue source that can be obtained without destroying external shape or function, is a source of elastic chondrocytes that show superb in vitro expansion and reliable differentiation capacity.