Open AccessConcise Review: Injectable Biomaterials for the Treatment of Myocardial Infarction and Peripheral Artery Disease: Translational Challenges and Progress
Author(s) -
Ungerleider Jessica L.,
Christman Karen L.
Publication year - 2014
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2014-0049
Subject(s) - biomaterial , myocardial infarction , medicine , regeneration (biology) , regenerative medicine , hyaluronic acid , tissue engineering , disease , stem cell , biomedical engineering , pathology , biology , microbiology and biotechnology , anatomy
This report summarizes the latest preclinical and clinical studies on injectable biomaterial therapies for myocardial infarction (MI) and peripheral artery disease (PAD). The study highlights the major challenges facing translation of these therapies to the clinic (e.g., regulatory, manufacturing, and delivery), with the purpose of increasing awareness of the barriers for translating novel biomaterial therapies for MI and PAD and facilitating more rapid translation of new biomaterial technologies.