Open AccessConcise Review: Unraveling Stem Cell Cocultures in Regenerative Medicine: Which Cell Interactions Steer Cartilage Regeneration and How?
Author(s) -
de Windt Tommy S.,
Hendriks Jeanine A.A.,
Zhao Xing,
Vonk Lucienne A.,
Creemers Laura B.,
Dhert Wouter J.A.,
Randolph Mark A.,
Saris Daniel B.F.
Publication year - 2014
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2013-0207
Subject(s) - chondrogenesis , cartilage , regeneration (biology) , regenerative medicine , mesenchymal stem cell , osteoarthritis , stem cell , microbiology and biotechnology , medicine , bioinformatics , biology , neuroscience , pathology , anatomy , alternative medicine
This review provides a systematic overview of the literature on stem cell cocultures with cartilage cells and tries to elucidate the mechanisms that lead to chondrogenesis. It could serve as a basis for research groups and clinicians aiming to design and implement combined cellular technologies for single‐stage cartilage repair and treatment or prevention of osteoarthritis.