Open AccessIntra‐Arterial Immunoselected CD34+ Stem Cells for Acute Ischemic Stroke
Author(s) -
Banerjee Soma,
Bentley Paul,
Hamady Mohammad,
Marley Stephen,
Davis John,
Shlebak Abdul,
Nicholls Joanna,
Williamson Deborah A.,
Jensen Steen L.,
Gordon Myrtle,
Habib Nagy,
Chataway Jeremy
Publication year - 2014
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2013-0178
Subject(s) - medicine , modified rankin scale , cd34 , stroke (engine) , stem cell , progenitor cell , middle cerebral artery , surgery , stem cell therapy , ischemia , ischemic stroke , transplantation , mechanical engineering , biology , engineering , genetics
In the first study of human subjects, the safety and feasibility of treatment with CD34+ cells delivered intra‐arterially in patients with acute ischemic stroke were determined. CD34+ cells were collected from the bone marrow of the subjects before being delivered by catheter angiography into the ipsilesional middle cerebral artery. Autologous CD34+ selected stem/progenitor cell therapy delivered intra‐arterially into the infarct territory can be achieved safely in patients with acute ischemic stroke.