Open AccessConcise Review: Reprogramming Strategies for Cardiovascular Regenerative Medicine: From Induced Pluripotent Stem Cells to Direct Reprogramming
Author(s) -
Budniatzky Inbar,
Gepstein Lior
Publication year - 2014
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2013-0163
Subject(s) - reprogramming , induced pluripotent stem cell , regenerative medicine , stem cell , biology , microbiology and biotechnology , computational biology , genetics , embryonic stem cell , cell , gene
The current review describes the different reprogramming strategies that can give rise to cardiomyocytes for regenerative medicine purposes. The advantages and shortcomings of each strategy for cardiac regeneration are discussed, along with the hurdles that need to be overcome on the road to clinical translation.