Open AccessConcise Review: Cell‐Based Strategies in Bone Tissue Engineering and Regenerative Medicine
Author(s) -
Ma Jinling,
Both Sanne K.,
Yang Fang,
Cui Fu-Zhai,
Pan Juli,
Meijer Gert J.,
Jansen John A.,
van den Beucken Jeroen J.J.P.
Publication year - 2014
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2013-0126
Subject(s) - regenerative medicine , tissue engineering , in vivo , cell , regeneration (biology) , microbiology and biotechnology , cell culture , biomedical engineering , stem cell , biology , medicine , biochemistry , genetics
Cellular strategies play an important role in bone tissue engineering and regenerative medicine (BTE/RM). Variability in cell culture procedures (e.g., cell types, cell isolation and expansion, cell seeding methods, and preculture conditions before in vivo implantation) may influence experimental outcome. The present review provides an overview of the critical procedures during in vitro and in vivo phases for cell‐based strategies (both monoculture and coculture) in BTE/RM.