Open AccessComparison of Human Adipose‐Derived Stem Cells Isolated from Subcutaneous, Omental, and Intrathoracic Adipose Tissue Depots for Regenerative Applications
Author(s) -
Russo Valerio,
Yu Claire,
Belliveau Paul,
Hamilton Andrew,
Flynn Lauren E.
Publication year - 2014
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2013-0125
Subject(s) - adipose tissue , adipogenesis , stem cell , tissue engineering , cd34 , biology , andrology , microbiology and biotechnology , medicine , endocrinology , genetics
A broader understanding was sought regarding the influence of specific adipose tissue depots on the isolated adipose‐derived stem cell (ASC) populations through a systematic comparison of donor‐matched abdominal subcutaneous fat and omentum, and donor‐matched pericardial adipose tissue and thymic remnant samples. Results suggest that depot selection is an important factor to consider when applying ASCs in tissue‐specific cell‐based regenerative therapies, and also highlight pericardial adipose tissue as a potential new ASC source.