Nestin Expression in End‐Stage Disease in Dystrophin‐Deficient Heart: Implications for Regeneration From Endogenous Cardiac Stem Cells | Zendy

Berry Suzanne E. | Zendy; Andruszkiewicz Peter | Zendy; Chun Ju Lan | Zendy; Hong Jun | Zendy

Open Access

Nestin Expression in End‐Stage Disease in Dystrophin‐Deficient Heart: Implications for Regeneration From Endogenous Cardiac Stem Cells

Author(s) -

Berry Suzanne E.,

Andruszkiewicz Peter,

Chun Ju Lan,

Hong Jun

Publication year - 2013

Publication title -

stem cells translational medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.781

H-Index - 71

eISSN - 2157-6580

pISSN - 2157-6564

DOI - 10.5966/sctm.2012-0174

Subject(s) - dystrophin , nestin , utrophin , biology , stem cell , duchenne muscular dystrophy , desmin , myocyte , cardiac marker , pathology , microbiology and biotechnology , medicine , vimentin , neural stem cell , immunology , troponin , immunohistochemistry , myocardial infarction , genetics

This study examined nestin‐positive stem cells in myocardium of dystrophin/utrophin‐deficient mice, a model for Duchenne muscular dystrophy. Findings indicate that new cardiomyocytes form in dystrophic heart, and nestin‐positive interstitial cells may generate them in addition to other cells of the cardiac lineage.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research