Humanized Culture of Periosteal Progenitors in Allogeneic Serum Enhances Osteogenic Differentiation and In Vivo Bone Formation | Zendy

Roberts Scott J. | Zendy; Owen Helen C. | Zendy; Tam Wai Long | Zendy; Solie Lien | Zendy; Van Cromphaut Sophie J. | Zendy; Van den Berghe Greet | Zendy; Luyten Frank P. | Zendy

Open Access

Humanized Culture of Periosteal Progenitors in Allogeneic Serum Enhances Osteogenic Differentiation and In Vivo Bone Formation

Author(s) -

Roberts Scott J.,

Owen Helen C.,

Tam Wai Long,

Solie Lien,

Van Cromphaut Sophie J.,

Van den Berghe Greet,

Luyten Frank P.

Publication year - 2014

Publication title -

stem cells translational medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.781

H-Index - 71

eISSN - 2157-6580

pISSN - 2157-6564

DOI - 10.5966/sctm.2012-0137

Subject(s) - progenitor cell , microbiology and biotechnology , runx2 , fetal bovine serum , alkaline phosphatase , stem cell , chemistry , bone resorption , immunology , biology , cell , endocrinology , biochemistry , enzyme

The authors attempted to apply alternative, xeno‐free culturing practices to a bone‐forming combination product of human periosteal progenitors on a clinically used calcium phosphate carrier. This study highlights the advantages of using humanized culture conditions for the expansion of human periosteal progenitors intended for bone regeneration.

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