Open AccessConcise Review: Acute Graft‐Versus‐Host Disease: Immunobiology, Prevention, and Treatment
Author(s) -
Sung Anthony D.,
Chao Nelson J.
Publication year - 2013
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2012-0115
Subject(s) - photopheresis , medicine , extracorporeal photopheresis , immunology , graft versus host disease , immunosuppression , disease , calcineurin , hematopoietic stem cell transplantation , stem cell , immune system , transplantation , lymphoma , pathology , biology , genetics
Graft‐versus‐host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplant associated with significant morbidity and mortality. This review focuses on the pathophysiology, clinical features, prevention, and treatment of acute GVHD.