Open AccessImpact of L-carnitine in narcolepsy treatment: a systematic review on the effectiveness and safety
Author(s) -
Cristina Salles,
Maria Clara Freitas,
Miguel Meira e Cruz
Publication year - 2022
Publication title -
sleep science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.582
H-Index - 17
eISSN - 1984-0659
pISSN - 1984-0063
DOI - 10.5935/1984-0063.20220004
Subject(s) - narcolepsy , sleep paralysis , cataplexy , excessive daytime sleepiness , tolerability , medicine , sleep disorder , carnitine , pediatrics , psychology , insomnia , psychiatry , modafinil , adverse effect
Studies have shown that narcolepsy patients may present with low serum acylcarnitine levels, demonstrating a dysfunctional beta fatty acid oxidation pathway in these patients.